In this episode of Bulletproof Radio, Juvenescence co-author Jim Mellon discusses the revolutionary changes that we’ve experienced in the last 20 years in the world of ageing. From scientific breakthroughs on the human genome to staying healthier with cellular agriculture, the conversation on ageing is changing so we can live healthier lives for longer.
The annual Abundance 360 strategic summit takes place every year at the end of January in Beverly Hills, California. Over three action-packed days, Peter prepares members for the year ahead, discussing transformative exponential technologies and what they mean for your business, industry, family and humanity.
What it is:
Every year since 2015, Peter has brought a curated cadre of longevity leaders to A360 to update members on the latest breakthroughs and opportunities. This unmissable module helps you understand the current state of longevity research and what’s coming to market in the decade ahead.
Why it’s important:
One of Peter’s greatest missions is to extend the healthy human lifespan, to make 100 years old the new 60. Constantly tracking innovation in the longevity and vitality field, he has founded a number of companies, and invested in numerous technologies in pursuit of this Moonshot. This module isn’t just about sharing research breakthroughs — it’s also about mindset. How does your decision-making change if you can reasonably expect to live another 30 to 50 healthy years?
Obesity plays a role in as many as 12 types of cancer, according to a major analysis of the causes of the disease.
The report by the World Cancer Research Fund (WCRF) found that while smoking remains the biggest cause of cancer, it may soon be overtaken by obesity in many countries, including the UK. In an earlier version of the report, released a decade ago, the WCRF identiﬁed seven cancers linked to obesity. Now, it says, the evidence points to 12: liver, ovaries,
prostate (advanced), stomach, mouth and throat, bowel, breast (post menopause), gall bladder, kidney, oesophagus, pancreas and womb. The report says that up to four in ten cancer cases are preventable, and urges non-smokers to adopt a ten-point health plan, which includes cutting down on bacon and processed meats, being physically active and reducing alcohol intake.
This is how much 20mg of paroxetine (Paxil in the US or Seroxat in the UK), an antidepressant that is now out of patent, costs around the world.
Aubrey de Grey of the SENS Research Foundation maintains an active schedule of presentations, and the interview here is one of a series of recent discussions in which he talks about timelines, funding, and progress in recent years. We’re in the midst of a tipping point of sorts, as the SENS view of rejuvenation research gathers more attention and legitimacy in the eyes of the public and various sources of funding. Senolytic therapies to clear senescent cells are well into the first stages of clinical development, with new compelling data for cellular senescence to contribute to specific age-related diseases arriving every month now. Targeting senescent cells for destruction was one of the strategies that de Grey started to advocate all the way back in 2002, when the research community was much less welcoming of any discussion of the treatment of aging as a medical condition, and there was little to no funding for such approaches despite the extensive supporting evidence. It doesn’t hurt to be proven right when it comes to reinforcing an agenda.